Bloodmyst Isle (aka Silvergale Isle) is the second of the two major isles of the Azuremyst Isles. North of the main island, Azuremyst Isle, Bloodmyst is often the next step in the journey for ambitious young draenei.

Bloodmyst Isle has been ravaged by radiation from the crashed draenei ship, the Exodar. Red crystals dot the land, and the eerie red mist for which the isle was renamed covers everything. Even the great pine trees which cover the island have taken on a crimson tinge. The creatures of the isle have mutated, in some cases becoming hostile. The draenei, hoping to find a way to restore the island, have set up an outpost known as Blood Watch near the center of the island.

Several giant creatures can be found on Bloodmyst Isle. The northwest of Bloodmyst Isle is home to a huge spider called Zarakh, its spawn grown to unnatural sizes due to contamination by the spaceship debris. Near the Vector Coil, blood elves have set up camp to control its energies and use it to empower their secret leader. Heroes of the draenei are called upon to bring her down. A smaller island off the coast to the northeast, called Wyrmscar Island, is now home to the ghost of a dragon named Razormaw.

Bloodmyst Isle has little historical information related to it. Originally known as Silvergale when the draenei first landed, it was once as beautiful as nearby Azuremyst Isle. The island was corrupted by blood red crystals from the draenei's dimensional ship, the Exodar. Blood-like liquid seeps from many of the crystals into the ground. The corruption from the liquid caused creatures and plants to become irradiated. The air was polluted with red-tinted mist from the red liquid. Due to the corruption the island was renamed "Bloodmyst". The island has lain out of view from central Kalimdor for a long time, and has largely been left to itself by the neighboring tauren and night elves. It is likely that this is why many enemies of the night elves, such as satyrs and naga, have found a haven here. When the Exodar crashed on Azuremyst Isle, several large pieces of the dimensional ship fell on Bloodmyst. These pieces are now used both by the draenei and by other creatures as a form of shelter.